1. Academic Validation
  2. Chemical constituents of Thai propolis

Chemical constituents of Thai propolis

  • Fitoterapia. 2013 Jul:88:96-100. doi: 10.1016/j.fitote.2013.04.008.
Sirivan Athikomkulchai 1 Suresh Awale 2 Nijsiri Ruangrungsi 3 Somsak Ruchirawat 4 Shigetoshi Kadota 5
Affiliations

Affiliations

  • 1 Faculty of Pharmacy, Srinakharinwirot University, Nakhon nayok, 26120, Thailand.
  • 2 Frontier Research Core for Life Sciences, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan; Institute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan. Electronic address: suresh@inm.u-toyama.ac.jp.
  • 3 Faculty of Pharmaceutical Sciences and College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • 4 Chulabhorn Research Institute, Vipavadee Rangsit Highway, Bangkok 10210, Thailand; Chemical Biology Program, Chulabhorn Graduate Institute, and the Center for Environmental Health, Toxicology and Management of Chemicals (ETM), Thailand.
  • 5 Institute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama 930-0194, Japan.
Abstract

Phytochemical investigation on the constituents of Thai propolis led the isolation of a new phenylallylflavanone, (7″S)-8-[1-(4'-hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]-(2S)-pinocembrin (1) and (E)-cinnamyl-(E)-cinnamylidenate (2) from methanolic extract of Thai propolis. Their structures were determined on the basis of extensive NMR spectroscopic analysis. In addition to this, 19 compounds (3-21) belonging to Flavonoids and phenolic esters were isolated and identified.

Keywords

Flavanoids; Phenolic esters; Phenylallylflavanones; Thai propolis.

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