2. Academic Validation
  3. Pharmacological treatment of acute heart failure: current treatment and new targets

Pharmacological treatment of acute heart failure: current treatment and new targets

  • Clin Pharmacol Ther. 2013 Oct;94(4):499-508. doi: 10.1038/clpt.2013.136.
J Pöss 1,  A Link,  M Böhm
Affiliations

Affiliation

  • 1 Universitätsklinikum des Saarlandes, Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Homburg/Saar, Germany.
PMID: 23863875 DOI: 10.1038/clpt.2013.136
Abstract

Acute heart failure (AHF) is defined as the rapid onset of, or changes in, the symptoms and signs of heart failure (HF). It is a life-threatening situation in which diagnosis and initiation of therapy are crucial. The treatment aims are to stabilize the patient, improve clinical symptoms, and increase long-term survival rates. Few treatments have been investigated in clinical trials. This review summarizes the principles of pharmacologic treatment, the underlying clinical trials, and new pharmacologic targets.

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