2. Academic Validation
  3. Two new sulfated sesquiterpenoids from Petasites tricholobus

Two new sulfated sesquiterpenoids from Petasites tricholobus

  • Yao Xue Xue Bao. 2014 Oct;49(10):1433-7.
Yong Zhang 1,  Yuan-Yuan Gao,  Qi Jia,  Fu-Jiang Guo,  Bo Li,  Zhi-Jian Xu,  Yi-Ming Li,  Wei-Liang Zhu,  Kai-Xian Chen
Affiliations

Affiliation

  • 1 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
PMID: 25577874
Abstract

Two new sulfated sesquiterpenoids, megastigman-7-ene-3, 5, 6, 9-tetrol-3-O-β-D-6'-sulfonated-glucopyranoside (1) and 3-O-β-D-6'-sulfonated-glucopyranosyl-6-(3-oxo-2-butenylidenyl)-1, 1, 5-trimethylcyclohexan-5-ol (2), along with one known sesquitepenoid compound icariside B1 (3) were isolated from the whole herb of Petasites tricholobus Franch. Their structures were identified by their chemical and spectroscopic characters. All obtained compounds were tested for their cytotoxicity against four Cancer cell lines.

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