1. Academic Validation
  2. Pathogenesis and clinical presentation of acute heart failure

Pathogenesis and clinical presentation of acute heart failure

  • Rev Esp Cardiol (Engl Ed). 2015 Apr;68(4):331-7. doi: 10.1016/j.rec.2015.02.001.
Piotr Ponikowski 1 Ewa A Jankowska 2
Affiliations

Affiliations

  • 1 Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland; Centre for Heart Diseases, Military Hospital, Wroclaw, Poland. Electronic address: piotrponikowski@4wsk.pl.
  • 2 Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland; Centre for Heart Diseases, Military Hospital, Wroclaw, Poland.
Abstract

Acute heart failure constitutes a heterogeneous clinical syndrome, whose pathophysiology is complex and not completely understood. Given the diversity of clinical presentations, several different pathophysiological mechanisms along with factors triggering circulatory decompensation are involved. This article discusses the available evidence on the pathophysiological phenomena attributed or/and associated with episodes of acute heart failure and describes different clinical profiles, which, from a clinical perspective, constitute a key element for therapeutic decision-making.

Keywords

Acute heart failure; Clinical profiles; Fisiopatología; Insuficiencia cardiaca aguda; Management; Pathophysiology; Perfiles clínicos; Tratamiento.

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