2. Academic Validation
  3. MDA-9/Syntenin Control

MDA-9/Syntenin Control

  • J Cell Physiol. 2016 Mar;231(3):545-50. doi: 10.1002/jcp.25136.
Julie V Philley 1,  Anbarasu Kannan 2,  Santanu Dasgupta 2
Affiliations

Affiliations

  • 1 Department of Medicine, The University of Texas Health Science Center at Tyler, Tyler, Texas.
  • 2 Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, Texas.
PMID: 26291527 DOI: 10.1002/jcp.25136
Abstract

MDA-9/Syntenin is a small PDZ domain containing scaffolding protein with diverse array of functions regulating membrane trafficking, cell adhesion, neural, and synaptic development, ubiquitination, and exosome biogenesis. An appreciable number of studies also established a pivotal role of MDA-9/Syntenin in Cancer development and progression. In this review, we will discuss the dynamic role of MDA-9/Syntenin in regulating normal and abnormal fate of various cellular processes.

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