2. Academic Validation
  3. Identification of Sternbin and Naringenin as Detoxified Metabolites from the Rice Flavanone Phytoalexin Sakuranetin by Pyricularia oryzae

Identification of Sternbin and Naringenin as Detoxified Metabolites from the Rice Flavanone Phytoalexin Sakuranetin by Pyricularia oryzae

  • Chem Biodivers. 2017 Feb;14(2). doi: 10.1002/cbdv.201600240.
Shun Katsumata 1,  Kazuho Hamana 1,  Kiyotaka Horie 2,  Hiroaki Toshima 1 2,  Morifumi Hasegawa 1 2
Affiliations

Affiliations

  • 1 College of Agriculture, Ibaraki University, 3-21-1 Chuo, Ami, Ibaraki, 300-0393, Japan.
  • 2 United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo, 183-8509, Japan.
PMID: 27647729 DOI: 10.1002/cbdv.201600240
Abstract

Sakuranetin (1) is a flavanone phytoalexin that has been reported to play an important role in disease resistance in rice Plants. The rice blast fungus Pyricularia oryzae (syn. Magnaporthe oryzae) has been reported to metabolize 1 to lower its Antifungal activity. Here, two flavanones, sternbin (2) and naringenin (3), were identified as metabolites of 1 in P. oryzae suspension culture by liquid chromatography tandem mass spectrometry (LC/MS/MS). The inhibition of 1, 2, and 3 on P. oryzae mycelial growth were 45%, 19%, and 19%, respectively, at a concentration of 100 μm. Thus, 2 and 3 are detoxified metabolites of 1 by P. oryzae.

Keywords

Pyricularia oryzae; Flavonoid; Phytoalexin; Rice.

Figures
Products
  • Cat. No.
    Product Name
    Description
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    Research Area
  • HY-N2754
    99.98%, Metabolite