2. Academic Validation
  3. Isolation and characterization of roridin E

Isolation and characterization of roridin E

  • Magn Reson Chem. 2017 Apr;55(4):337-340. doi: 10.1002/mrc.4539.
Clark D Ridge 1,  Eugene P Mazzola 1,  Martyn P Coles 2,  Simon F R Hinkley 2
Affiliations

Affiliations

  • 1 Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA.
  • 2 The Ferrier Research Institute, School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington, New Zealand.
PMID: 27737497 DOI: 10.1002/mrc.4539
Abstract

The commonly occurring, high-cytotoxicity Macrolide roridin E has been re-isolated from Stachybotrys chartarum and characterized by 1-D and 2-D NMR spectroscopy. Assignment of the spectral data for roridin E revealed differences from the accepted literature, and spectra are reported herein to aid in future identification. For the first time confirmation of structure was provided by a crystallographic solution for roridin E. Copyright © 2016 John Wiley & Sons, Ltd.

Keywords

NMR analysis; roridin E; trichothecene.

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