2. Academic Validation
  3. Acidic in vivo metabolites of cannabinol isolated from rat faeces

Acidic in vivo metabolites of cannabinol isolated from rat faeces

  • J Pharm Pharmacol. 1978 Sep;30(9):554-7. doi: 10.1111/j.2042-7158.1978.tb13322.x.
A W Yisak,  M Widman,  S Agurell
PMID: 29093 DOI: 10.1111/j.2042-7158.1978.tb13322.x
Abstract

Six acidic metabolites were isolated from rat faeces and identified by gas chromatographymass spectrometry and proton magnetic resonance. Cannabinol-7-oic acid was the most abundant acidic metabolite isolated. Others present in decreasing order of prominence were 1"-hydroxy-, 4"-hydroxy-, 3"-hydroxycannabinol-7-oic acid, cannabinol-3"-one-7-oic acid and 2"-hydroxycannabinol-7-oic acid.

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