2. Academic Validation
  3. Antibacterial and antifungal activity of phytosterols and methyl dehydroabietate of Norway spruce bark extracts

Antibacterial and antifungal activity of phytosterols and methyl dehydroabietate of Norway spruce bark extracts

  • J Biotechnol. 2018 Sep 20;282:18-24. doi: 10.1016/j.jbiotec.2018.06.340.
Zuzana Burčová 1,  František Kreps 2,  Mária Greifová 2,  Michal Jablonský 3,  Aleš Ház 3,  Štefan Schmidt 2,  Igor Šurina 3
Affiliations

Affiliations

  • 1 Department of Food Technology, Institute of Food Science and Nutrition, Faculty of Chemical and Food Technology of the Slovak University of Technology in Bratislava, Radlinského 9, Bratislava, 812 37, Slovak Republic. Electronic address: zuzana.burcova@stuba.sk.
  • 2 Department of Food Technology, Institute of Food Science and Nutrition, Faculty of Chemical and Food Technology of the Slovak University of Technology in Bratislava, Radlinského 9, Bratislava, 812 37, Slovak Republic.
  • 3 Department of Wood, Pulp, and Paper, Institute of Natural and Synthetic Polymers, Faculty of Chemical and Food Technology of the Slovak University of Technology in Bratislava, Radlinského 9, Bratislava, 812 37, Slovak Republic.
PMID: 29940188 DOI: 10.1016/j.jbiotec.2018.06.340
Abstract

The current study focuses on the analysis of in vitro biological activity of extract from bark of Norway spruce (Picea Abies), which can find potential application in food and cosmetic industry and pharmacology. Milled bark was subjected to Soxhlet extraction and supercritical fluid extraction to obtain two ethanol extracts. These extracts were further used to obtain their pre-extracts to n-hexane. It was investigated whether beta-sitosterol exhibits bacteriostatic activity necessary to observe antimicrobial and Antifungal activity of methyl dehydroabiatate. This synergic effect and bacteriostatic activity of beta-sitosterol have not been previously reported. The greatest inhibition zone of n-hexane pre-extracts was confirmed in bacterium Pseudomonas aeruginosa (0,9 - 1,5 cm) and yeast Alternaria alternata (0,7 - 1,6 cm). It is novel, the antioxidant, antimicrobial and Antifungal activity of spruce bark extracts assessed in terms of food and cosmetic fortification.

Keywords

Antifungal; Antimicrobial; Antioxidants; Bioactive plants; Dehydroabietic acid; Sterols.

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