2. Academic Validation
  3. Pyrrole: An insight into recent pharmacological advances with structure activity relationship

Pyrrole: An insight into recent pharmacological advances with structure activity relationship

  • Eur J Med Chem. 2018 Sep 5:157:527-561. doi: 10.1016/j.ejmech.2018.08.002.
Shujauddin Ahmad 1,  Ozair Alam 2,  Mohd Javed Naim 1,  Mohammad Shaquiquzzaman 1,  M Mumtaz Alam 1,  Muzaffar Iqbal 3
Affiliations

Affiliations

  • 1 Medicinal Chemistry and Molecular Modelling Lab, Dept. of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard Nagar, New Delhi, 62, India.
  • 2 Medicinal Chemistry and Molecular Modelling Lab, Dept. of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, Hamdard Nagar, New Delhi, 62, India. Electronic address: dr.ozairalam@gmail.com.
  • 3 Dept. of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
PMID: 30119011 DOI: 10.1016/j.ejmech.2018.08.002
Abstract

Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for the generation of library of enormous lead molecules. Owing to its vast pharmacological profile, pyrrole and its analogues have drawn much attention of the researchers/chemists round the globe to be explored exhaustively for the benefit of mankind. This review focusses on recent advancements; pertaining to pyrrole scaffold, discussing various aspects of structure activity relationship and its bioactivities.

Keywords

Anticancer; Antimicrobial; Pyrrole; Structure activity relationship.

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