2. Academic Validation
  3. Green recipes to quinoline: A review

Green recipes to quinoline: A review

  • Eur J Med Chem. 2019 Feb 15:164:121-170. doi: 10.1016/j.ejmech.2018.11.026.
Lalit Mohan Nainwal 1,  Sharba Tasneem 1,  Wasim Akhtar 1,  Garima Verma 1,  Mohammed Faraz Khan 1,  Suhel Parvez 2,  Mohammad Shaquiquzzaman 1,  Mymoona Akhter 1,  Mohammad Mumtaz Alam 3
Affiliations

Affiliations

  • 1 Drug Design & Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India.
  • 2 Department of Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India.
  • 3 Drug Design & Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India. Electronic address: drmmalam@gmail.com.
PMID: 30594028 DOI: 10.1016/j.ejmech.2018.11.026
Abstract

The quinoline core possesses a vast number of biological activities such as Anticancer, antimalarial, antimicrobial, Antifungal, antitubercular and antileishmanial. The conventional classical synthetic methods require the use of expensive and harsh conditions such as high temperature. Currently the scientific communities are searching new methodology to eliminate the use of chemicals, Solvents and catalysts, which are hazardous to human health as well as to environment. This review provides a concise overview of new dimensions of green chemistry approaches in designing quinoline scaffold that would encourage the researchers towards green chemistry as well as future application of these greener, non-toxic, environment friendly methods in designing quinoline scaffold.

Keywords

Friedländer reaction; Green chemistry; Microwave irradiation; Multicomponent reactions; Quinolines.

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