2. Academic Validation
  3. Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux

Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux

  • J Diabetes. 2019 Oct;11(10):826-836. doi: 10.1111/1753-0407.12914.
Juan Jin 1 2,  Jianguang Gong 1 2,  Li Zhao 1 2,  Hongjuan Zhang 1 2,  Qiang He 1 2,  Xinxin Jiang 1 2
Affiliations

Affiliations

  • 1 Department of Nephrology, Zhejiang Provincial People's Hospital, Zhejiang, China.
  • 2 Department of Nephrology, People's Hospital of Hangzhou Medical College, Zhejiang, China.
PMID: 30864227 DOI: 10.1111/1753-0407.12914
Keywords

AKT/mTOR信号通路; AKT/mammalian target of (mTOR) signaling; HMGB1; epithelial-mesenchymal transdifferentiation; high mobility group box 1 (HMGB1); podocyte apoptosis; rapamycin; 上皮-间充质转分化; 足细胞凋亡; 雷帕霉素.

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