2. Academic Validation
  3. Chemical Constituents of Vigna luteola and Their Anti-inflammatory Bioactivity

Chemical Constituents of Vigna luteola and Their Anti-inflammatory Bioactivity

  • Molecules. 2019 Apr 8;24(7):1371. doi: 10.3390/molecules24071371.
Sio-Hong Lam 1,  Yue-Chiun Li 2,  Ping-Chung Kuo 3,  Tsong-Long Hwang 4 5 6,  Mei-Lin Yang 7,  Chien-Chiao Wang 8,  Jason T C Tzen 9
Affiliations

Affiliations

  • 1 School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. shlam@mail.ncku.edu.tw.
  • 2 Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. ycli0126@gmail.com.
  • 3 School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. z10502016@email.ncku.edu.tw.
  • 4 Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. htl@mail.cgu.edu.tw.
  • 5 Research Center for Industry of Human Ecology, Research Center for Chinese Herbal Medicine, and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan. htl@mail.cgu.edu.tw.
  • 6 Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan. htl@mail.cgu.edu.tw.
  • 7 School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. L3891104@nckualumni.org.tw.
  • 8 Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. D0501502@cgu.edu.tw.
  • 9 Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. tctzen@dragon.nchu.edu.tw.
PMID: 30965630 DOI: 10.3390/molecules24071371
Abstract

Seventy-three compounds were identified from the methanol extract of V. luteola, and among these, three new (1⁻3) were characterized by spectroscopic and mass spectrometric analyses. The isolated constituents were assessed for anti-inflammatory potential evaluation, and several purified principles exhibited significant superoxide anion and Elastase inhibitory effects.

Keywords

elastase release; fabaceae; sesquiterpenoid; superoxide anion generation.

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