2. Academic Validation
  3. RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7

RIFM fragrance ingredient safety assessment, 1,2-dimethoxybenzene, CAS Registry Number 91-16-7

  • Food Chem Toxicol. 2019 Aug:130 Suppl 1:110618. doi: 10.1016/j.fct.2019.110618.
A M Api 1,  D Belsito 2,  D Botelho 1,  M Bruze 3,  G A Burton Jr 4,  J Buschmann 5,  M L Dagli 6,  M Date 1,  W Dekant 7,  C Deodhar 1,  M Francis 1,  A D Fryer 8,  L Jones 1,  K Joshi 1,  S La Cava 1,  A Lapczynski 1,  D C Liebler 9,  D O'Brien 1,  A Patel 1,  T M Penning 10,  G Ritacco 1,  J Romine 1,  N Sadekar 1,  D Salvito 1,  T W Schultz 11,  I G Sipes 12,  G Sullivan 13,  Y Thakkar 1,  Y Tokura 14,  S Tsang 1
Affiliations

Affiliations

  • 1 Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA.
  • 2 Member RIFM Expert Panel, Columbia University Medical Center, Department of Dermatology, 161 Fort Washington Ave., New York, NY, 10032, USA.
  • 3 Member RIFM Expert Panel, Malmo University Hospital, Department of Occupational & Environmental Dermatology, Sodra Forstadsgatan 101, Entrance 47, Malmo, SE-20502, Sweden.
  • 4 Member RIFM Expert Panel, School of Natural Resources & Environment, University of Michigan, Dana Building G110, 440 Church St., Ann Arbor, MI, 58109, USA.
  • 5 Member RIFM Expert Panel, Fraunhofer Institute for Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625, Hannover, Germany.
  • 6 Member RIFM Expert Panel, University of Sao Paulo, School of Veterinary Medicine and Animal Science, Department of Pathology, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo, CEP 05508-900, Brazil.
  • 7 Member RIFM Expert Panel, University of Wuerzburg, Department of Toxicology, Versbacher Str. 9, 97078, Würzburg, Germany.
  • 8 Member RIFM Expert Panel, Oregon Health Science University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA.
  • 9 Member RIFM Expert Panel, Vanderbilt University School of Medicine, Department of Biochemistry, Center in Molecular Toxicology, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN, 37232-0146, USA.
  • 10 Member of RIFM Expert Panel, University of Pennsylvania, Perelman School of Medicine, Center of Excellence in Environmental Toxicology, 1316 Biomedical Research Building (BRB) II/III, 421 Curie Boulevard, Philadelphia, PA, 19104-3083, USA.
  • 11 Member RIFM Expert Panel, The University of Tennessee, College of Veterinary Medicine, Department of Comparative Medicine, 2407 River Dr., Knoxville, TN, 37996- 4500, USA.
  • 12 Member RIFM Expert Panel, Department of Pharmacology, University of Arizona, College of Medicine, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ, 85724-5050, USA.
  • 13 Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ, 07677, USA. Electronic address: gsullivan@rifm.org.
  • 14 Member RIFM Expert Panel, The Journal of Dermatological Science (JDS), Editor-in-Chief, Professor and Chairman, Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, 431-3192, Japan.
PMID: 31233873 DOI: 10.1016/j.fct.2019.110618
Keywords

Environmental safety; Genotoxicity; Local respiratory toxicity; Phototoxicity/photoallergenicity; Repeated dose, developmental, and reproductive toxicity; Skin sensitization.

Figures
Products