2. Academic Validation
  3. Structures of New Alkaloids from Rain Forest Trees Galbulimima belgraveana and Galbulimima baccata in Papua New Guinea, Indonesia, and Northern Australia

Structures of New Alkaloids from Rain Forest Trees Galbulimima belgraveana and Galbulimima baccata in Papua New Guinea, Indonesia, and Northern Australia

  • ACS Omega. 2018 Feb 14;3(2):1912-1921. doi: 10.1021/acsomega.7b02065.
Ping Lan 1,  Anthony J Herlt 2,  Anthony C Willis 2,  Walter C Taylor 3,  Lewis N Mander 2
Affiliations

Affiliations

  • 1 Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China.
  • 2 Research School of Chemistry, Australian National University, Canberra, Australian Capital Territory 2601, Australia.
  • 3 School of Chemistry, University of Sydney, Sydney, New South Wales 2006, Australia.
PMID: 31458503 DOI: 10.1021/acsomega.7b02065
Abstract

Following on our 60-year research on the chemical constituents of the rain forest trees Galbulimima belgraveana and Galbulimima baccata, we report the isolation of seven new alkaloids: GB14 (14), GB22 (15), GB25 (16), GB21 (17), GB23 (18), GB24 (19), and GB26 (20). Their structures were elucidated by a combination of spectroscopic analyses and single-crystal X-ray crystallography, as well as structure degradation and interconversion. The newly isolated Alkaloids are precursors or derivatives of the known family members from our early studies and could be intermediates in the biosynthesis of the Galbulimima Alkaloids. Therefore, the present study has expanded the range of structures in this family of Alkaloids and provided some missing links in the biosynthetic sequences.

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