METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing

Affiliations

• 1 Division of Newborn Medicine and Program in Epigenetics, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA.
• 2 Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
• 3 Bioinformatics Interdepartmental Graduate Program, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
• 4 College of Science, Northeastern University, 360 Huntington Ave., Boston, MA, 02115, USA.
• 5 Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
• 6 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
• 7 Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
• 8 Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
• 9 Division of Newborn Medicine and Program in Epigenetics, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA. yshi@hms.harvard.edu.
• # Contributed equally.