2. Academic Validation
  3. Bitter compounds in two Tricholoma species, T. aestuans and T. virgatum

Bitter compounds in two Tricholoma species, T. aestuans and T. virgatum

  • J Antibiot (Tokyo). 2020 Oct;73(10):697-701. doi: 10.1038/s41429-020-0338-x.
Yumiko Oba 1,  Makoto Urai 2,  Jing Wu 3,  Motohiro Tomizawa 2,  Hirokazu Kawagishi 1 3,  Kimiko Hashimoto 4
Affiliations

Affiliations

  • 1 Graduate School of Science and Technology, Shizuoka University, Shizuoka, Japan.
  • 2 Department of Chemistry for Life Sciences and Agriculture, Faculty of Life Sciences, Tokyo University of Agriculture, Tokyo, Japan.
  • 3 Research Institute of Green Science and Technology, Shizuoka University, Shizuoka, Japan.
  • 4 Department of Chemistry for Life Sciences and Agriculture, Faculty of Life Sciences, Tokyo University of Agriculture, Tokyo, Japan. kh206428@nodai.ac.jp.
PMID: 32576949 DOI: 10.1038/s41429-020-0338-x
Abstract

Lascivol was identified as the bitter compound in two Tricholoma species, T. aestuans and T. virgatum, and was previously isolated from the European mushroom T. lascivum. The structure of lascivol was previously solved by X-ray crystallographical analysis but its stereochemistry at C3 remained ambiguous. We thus re-examined the absolute configuration of C3 bearing a hydroxy group using the modified Mosher's method.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-120735
    Bitter Compound