2. Academic Validation
  3. Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma

Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma

  • Signal Transduct Target Ther. 2020 Sep 14;5(1):200. doi: 10.1038/s41392-020-00309-1.
Juan Liu  # 1 2,  Qianmao Liang  # 1 2,  Aoli Wang  # 1 3,  Fengming Zou  # 1 3,  Ziping Qi 1 3,  Kailin Yu 1,  Qingwang Liu 1 3 4 5,  Cheng Chen 1 2 3,  Jing Liu 6 7 8,  Qingsong Liu 9 10 11 12 13 14
Affiliations

Affiliations

  • 1 Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • 2 University of Science and Technology of China, 230036, Hefei, Anhui, P. R. China.
  • 3 Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China.
  • 4 Precision Medicine Research Laboratory of Anhui Province, 230088, Hefei, Anhui, P. R. China.
  • 5 Precision Targeted Therapy Discovery Center, Institute of Technology Innovation, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230088, Hefei, Anhui, P. R. China.
  • 6 Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China. jingliu@hmfl.ac.cn.
  • 7 University of Science and Technology of China, 230036, Hefei, Anhui, P. R. China. jingliu@hmfl.ac.cn.
  • 8 Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China. jingliu@hmfl.ac.cn.
  • 9 Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China. qsliu97@hmfl.ac.cn.
  • 10 University of Science and Technology of China, 230036, Hefei, Anhui, P. R. China. qsliu97@hmfl.ac.cn.
  • 11 Hefei Cancer Hospital, Chinese Academy of Sciences, 230031, Hefei, Anhui, P. R. China. qsliu97@hmfl.ac.cn.
  • 12 Precision Medicine Research Laboratory of Anhui Province, 230088, Hefei, Anhui, P. R. China. qsliu97@hmfl.ac.cn.
  • 13 Precision Targeted Therapy Discovery Center, Institute of Technology Innovation, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230088, Hefei, Anhui, P. R. China. qsliu97@hmfl.ac.cn.
  • 14 Institutes of Physical Science and Information Technology, Anhui University, 230601, Hefei, Anhui, P. R. China. qsliu97@hmfl.ac.cn.
  • # Contributed equally.
PMID: 32929063 DOI: 10.1038/s41392-020-00309-1
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