2. Academic Validation
  3. Fibronectin in development and wound healing

Fibronectin in development and wound healing

  • Adv Drug Deliv Rev. 2021 Mar:170:353-368. doi: 10.1016/j.addr.2020.09.005.
Jennifer Patten 1,  Karin Wang 2
Affiliations

Affiliations

  • 1 Department of Bioengineering, Temple University, Philadelphia, PA, USA.
  • 2 Department of Bioengineering, Temple University, Philadelphia, PA, USA. Electronic address: karin.wang@temple.edu.
PMID: 32961203 DOI: 10.1016/j.addr.2020.09.005
Abstract

Fibronectin structure and composition regulate contextual cell signaling. Recent advances have been made in understanding fibronectin and its role in tissue organization and repair. This review outlines fibronectin splice variants and their functions, evaluates potential therapeutic strategies targeting or utilizing fibronectin, and concludes by discussing potential future directions to modulate fibronectin function in development and wound healing.

Keywords

Development; Fibronectin; Isoforms; Regeneration; Splice variants; Wound healing.

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