2. Academic Validation
  3. Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease

Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease

  • Gut. 2022 Apr;71(4):842-844. doi: 10.1136/gutjnl-2021-324727.
Nicolas Hohmann 1,  Fabian Schröder 2,  Bernardo Moreira 2,  Haidong Teng 2,  Jürgen Burhenne 1,  Thomas Bruckner 3,  Sebastian Mueller 2,  Walter E Haefeli # 1,  Helmut K Seitz # 4
Affiliations

Affiliations

  • 1 Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University, Heidelberg, Germany.
  • 2 Department of Medicine, Krankenhaus Salem, Heidelberg, Baden-Württemberg, Germany.
  • 3 Institute of Medical Biometry and Informatics, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.
  • 4 Krankenhaus Salem, Heidelberg, Baden-Württemberg, Germany helmut_karl.seitz@urz.uni-heidelberg.de.
  • # Contributed equally.
PMID: 33972357 DOI: 10.1136/gutjnl-2021-324727
Keywords

alcohol; alcoholic liver disease; clinical trials; cytochrome p450.

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