2. Academic Validation
  3. Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model

Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model

  • Signal Transduct Target Ther. 2022 Apr 16;7(1):123. doi: 10.1038/s41392-022-00963-7.
Ruxue Zhang  # 1 2,  Yumin Zhang  # 1,  Wei Zheng  # 2 3,  Weijuan Shang 1,  Yan Wu 1,  Ning Li 4,  Jun Xiong 4,  Hualiang Jiang 2 3,  Jingshan Shen 2 3,  Gengfu Xiao 1 2,  Yuanchao Xie 5 6,  Leike Zhang 7 8
Affiliations

Affiliations

  • 1 State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
  • 2 University of Chinese Academy of Sciences, Beijing, 100049, China.
  • 3 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • 4 Shanghai Junshi Biosciences Co., Ltd., Shanghai, 200126, China.
  • 5 Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. xieyuanchao@simm.ac.cn.
  • 6 Lingang Laboratory, Shanghai, 200031, China. xieyuanchao@simm.ac.cn.
  • 7 State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China. zhangleike@wh.iov.cn.
  • 8 University of Chinese Academy of Sciences, Beijing, 100049, China. zhangleike@wh.iov.cn.
  • # Contributed equally.
PMID: 35429988 DOI: 10.1038/s41392-022-00963-7
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