2. Academic Validation
  3. Bagougeramines A and B, new nucleoside antibiotics produced by a strain of Bacillus circulans. II. Physico-chemical properties and structure determination

Bagougeramines A and B, new nucleoside antibiotics produced by a strain of Bacillus circulans. II. Physico-chemical properties and structure determination

  • J Antibiot (Tokyo). 1986 Aug;39(8):1041-6. doi: 10.7164/antibiotics.39.1041.
A Takahashi,  D Ikeda,  H Naganawa,  Y Okami,  H Umezawa
PMID: 3759654 DOI: 10.7164/antibiotics.39.1041
Abstract

Bagougeramines A and B obtained as sulfates were soluble in water and positive to Sakaguchi, chlorine-tolidine and ninhydrin color reactions. Their structures were determined by acid hydrolysis and spectroscopic analysis. Structurally they were closely related to gougerotin and they contained the guanidino-D-alanine instead of the serine residue in gougerotin. Bagougeramine B had the spermidine instead of the 6'-NH2 in structure of bagougeramine A.

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