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  3. Tetraniliprole risk assessment: Unveiling a hidden threat for managing a generalist herbivore

Tetraniliprole risk assessment: Unveiling a hidden threat for managing a generalist herbivore

  • Environ Res. 2024 Sep 1:256:119273. doi: 10.1016/j.envres.2024.119273.
Cheng Qu 1,  Yunyi Li 2,  Qianyuan Zhan 2,  Jinda Wang 3,  Chen Luo 2,  Raul Narciso C Guedes 4,  Ran Wang 5
Affiliations

Affiliations

  • 1 Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China; Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China, Beijing, 100097, China.
  • 2 Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.
  • 3 National Engineering Research Center of Sugarcane, Fujian Agricultural and Forestry University, Fuzhou, 350002, China. Electronic address: jdwang@fafu.edu.cn.
  • 4 Departamento de Entomologia, Universidade Federal de Viçosa, Viçosa, MG, 36570-900, Brazil.
  • 5 Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China; Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China, Beijing, 100097, China. Electronic address: wangran@ippbaafs.cn.
PMID: 38821465 DOI: 10.1016/j.envres.2024.119273
Abstract

Insecticide resistance poses a significant challenge in managing generalist herbivores such as the tobacco cutworm (TCW), Spodoptera litura. This study investigates the potential risks associated with using the novel diamide insecticide tetraniliprole to control TCW. A tetraniliprole-resistant strain was developed through twelve generations of laboratory selection, indicating an intermediate risk of resistance development. Field monitoring in China revealed a significant incidence of resistance, particularly in the Nanchang (NC) population (>100-fold). Tetraniliprole showed moderate to high cross-resistance to multiple insecticides and was autosomally inherited with incomplete dominance, controlled by multiple genes, some of which belong to the Cytochrome P450 family associated with enhanced detoxification. Life table studies indicated transgenerational hormesis, stimulating TCW female fecundity and increasing population net reproduction rates (R0). These findings suggest a potential for pest resurgence under tetraniliprole use. The integrated risk assessment provides a basis for the sustainable management of TCW using tetraniliprole.

Keywords

Baseline of susceptibility; Biochemical mechanism; Mode of inheritance; Realized heritability; Tobacco cutworm; Transgenerational hormesis.

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