1. Academic Validation
  2. beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase

beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase

  • J Bacteriol. 1985 Dec;164(3):1350-2. doi: 10.1128/jb.164.3.1350-1352.1985.
W A Whalen M D Wang C M Berg
Abstract

beta-Chloro-L-alanine, an amino acid analog which inhibits a number of Enzymes, reversibly inhibited the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, accounted for the isoleucine-plus-valine requirement of E. coli in the presence of beta-chloro-L-alanine.

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