2. Academic Validation
  3. Structural studies on pyrrolomycins C, D and E

Structural studies on pyrrolomycins C, D and E

  • J Antibiot (Tokyo). 1983 Nov;36(11):1483-9. doi: 10.7164/antibiotics.36.1483.
M Koyama,  N Ezaki,  T Tsuruoka,  S Inouye
PMID: 6654758 DOI: 10.7164/antibiotics.36.1483
Abstract

Pyrrolomycins C, D and E are new members of the pyrrolomycin group of Antibiotics produced by an Actinosporangium sp. The structures of pyrrolomycins C and D were determined to be 2,3-dichloro-5-(3',5'-dichloro-2'-hydroxybenzoyl)pyrrole and 2,3,4-trichloro-5-(3',5'-dichloro-2'-hydroxybenzoyl)pyrrole, respectively, by means of spectroscopic and synthetic approaches while that of pyrrolomycin E was shown to be 5-chloro-2-(3',5'-dichloro-2'-hydroxyphenyl)-3-nitropyrrole by spectroscopic data.

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