2. Academic Validation
  3. DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells

DNA-protein cross-linking by the mycotoxin, botryodiplodin, in mammalian cells

  • Carcinogenesis. 1982;3(2):211-4. doi: 10.1093/carcin/3.2.211.
Y Moulé,  F Renauld,  N Darracq,  C Douce
PMID: 7067047 DOI: 10.1093/carcin/3.2.211
Abstract

Botryodiplodin, a mycotoxin isolated from a strain of Penicillium roqueforti, induces DNA-protein cross-links in mammalian cells. This action depends upon the presence of the hydroxyl group at the position 2 of the molecule. The mechanism involved in the formation of cross-linkings is discussed.

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