2. Academic Validation
  3. In vitro antibacterial activity of different clotrimazole formulations

In vitro antibacterial activity of different clotrimazole formulations

  • Chemotherapy. 1982;28 Suppl 1:32-6. doi: 10.1159/000238149.
K Schaller
PMID: 7160238 DOI: 10.1159/000238149
Abstract

The Antibacterial activity of two different clotrimazole formulations was tested in vitro. A neutral vaginal tablet with 100 mg active ingredient has a partial bactericidal effect on gram-positive bacteria. A new formula containing 500 mg clotrimazole and lactic acid, designed for a one-dose therapy of vulvovaginal mycoses, shows an improved bactericidal activity against gram-positive bacteria and, owing to the lactic acid content, a broad bactericidal effect on gram-negative species.

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