2. Academic Validation
  3. Antitumor agents from bohemic acid complex, III. The isolation of marcellomycin, musettamycin, rudolphomycin, mimimycin, collinemycin, alcindoromycin, and bohemamine

Antitumor agents from bohemic acid complex, III. The isolation of marcellomycin, musettamycin, rudolphomycin, mimimycin, collinemycin, alcindoromycin, and bohemamine

  • J Nat Prod. 1980 Mar-Apr;43(2):242-58. doi: 10.1021/np50008a003.
D E Nettleton Jr,  D M Balitz,  T W Doyle,  W T Bradner,  D L Johnson,  F A O'Herron,  R H Schreiber,  A B Coon,  J E Moseley,  R W Myllymaki
PMID: 7381507 DOI: 10.1021/np50008a003
Abstract

Six anthracycline antitumor agents, marcellomycin, musettamycin, rudolphomycin, alcindoromycin, collinemycin, and mimimycin, have now been isolated from bohemic acid complex. This has been achieved by classical column chromatography with Sephadex LH-20 and ammonia-neutralized silica and by analytical and prepatative hplc techniques with normal phase systems containing aqueous ammonia.

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