2. Academic Validation
  3. Production of rhodomycins in Streptomyces griseoruber 4620

Production of rhodomycins in Streptomyces griseoruber 4620

  • Folia Microbiol (Praha). 1980;25(6):464-6. doi: 10.1007/BF02897211.
M Podojil,  M Blumauerová,  V Prikrylová,  Z Vanĕk,  G F Gauze,  T S Maksimova
PMID: 7439844 DOI: 10.1007/BF02897211
Abstract

The strain Streptomyces griseoruber 4620 produces, besides the anthracycline Antibiotics beromycins, some Other anthracyclines of the rhodomycin type. Twelve isolates exhibiting a higher Antibiotic activity (up to 2.5X), as compared to the parent strain, were obtained after a spontaneous selection. The following species were isolated from the hydrolysate of mycelial extract: beta-rhodomycinone, beta-isorhodomycinone, alpha 2-rhodomycinone, epsilon-rhodomycinone and 10-deoxy-beta-rhodomycinone, which has not yet been described.

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