2. Academic Validation
  3. Cytotoxic diterpenoids from Isodon megathyrsus

Cytotoxic diterpenoids from Isodon megathyrsus

  • J Nat Prod. 1994 Oct;57(10):1424-9. doi: 10.1021/np50112a012.
H D Sun 1,  Z W Lin,  F D Niu,  L Z Lin,  H Chai,  J M Pezzuto,  G A Cordell
Affiliations

Affiliation

  • 1 Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming, Yunnan, People's Republic of China.
PMID: 7528785 DOI: 10.1021/np50112a012
Abstract

A new diterpenoid, megathyrin A, together with three known compounds, rabdocoetsins B, C, and D, were isolated from the leaves of Isodon megathyrsus, and their structures and nmr spectral data were assigned by a combination of one- and two-dimensional nmr techniques. These compounds displayed significant cytotoxic activity.

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