2. Academic Validation
  3. Chivosazol A, a new inhibitor of eukaryotic organisms isolated from myxobacteria

Chivosazol A, a new inhibitor of eukaryotic organisms isolated from myxobacteria

  • J Antibiot (Tokyo). 1995 Sep;48(9):962-6. doi: 10.7164/antibiotics.48.962.
H Irschik 1,  R Jansen,  K Gerth,  G Höfle,  H Reichenbach
Affiliations

Affiliation

  • 1 GBF, Gesellschaft für Biotechnologische Forschung, Departments of Biology of Natural Products, Braunschweig, Germany.
PMID: 7592063 DOI: 10.7164/antibiotics.48.962
Abstract

A new Antibiotic, chivosazol, was isolated from the culture broth of the myxobacterium Sorangium cellulosum strain So ce12. It is a macrocyclic ring with one oxazol ring and a glycosidically bound 6-deoxyglucose (quinovose) at C-11. The Antibiotic shows antimicrobial activity against yeasts and filamentous fungi, and is especially potent against mammalian cells. It was not active against bacteria.

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