2. Academic Validation
  3. Absolute configuration of a new mosquito repellent, (+)-eucamalol and the repellent activity of its epimer

Absolute configuration of a new mosquito repellent, (+)-eucamalol and the repellent activity of its epimer

  • Biosci Biotechnol Biochem. 1995 Jun;59(6):1139-41. doi: 10.1271/bbb.59.1139.
A Satoh 1,  H Utamura,  T Nakade,  H Nishimura
Affiliations

Affiliation

  • 1 Department of Bioscience and Technology, School of Engineering, Hokkaido Tokai University, Sapporo, Japan.
PMID: 7613002 DOI: 10.1271/bbb.59.1139
Abstract

(+)-Eucamalol (1) and (-)-1-epi-eucamalol (2) were synthesized from (S)-(-)-perillaldehyde to determine the absolute configuration of 1, the structure of natural (+)-eucamalol being determined to be (1R,6R)-(+)-3-formyl-6-isopropyl-2-cyclohexen-1-ol. (+)-Eucamolol (1) and its 1-epimer (2) exhibited significant repellent activity against Aedes albopictus, and inhibited its feeding as well as DEET.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-N3878
    Natural Product