2. Academic Validation
  3. Albaflavenone, a sesquiterpene ketone with a zizaene skeleton produced by a streptomycete with a new rope morphology

Albaflavenone, a sesquiterpene ketone with a zizaene skeleton produced by a streptomycete with a new rope morphology

  • J Antibiot (Tokyo). 1994 Apr;47(4):434-9. doi: 10.7164/antibiotics.47.434.
H Gürtler 1,  R Pedersen,  U Anthoni,  C Christophersen,  P H Nielsen,  E M Wellington,  C Pedersen,  K Bock
Affiliations

Affiliation

  • 1 Novo Nordisk A/S, Novo Alle, Bagsvaerd, Denmark.
PMID: 8195043 DOI: 10.7164/antibiotics.47.434
Abstract

A novel Antibiotic alpha,beta-unsaturated sesquiterpene ketone, albaflavenone with a zizaene skeleton was isolated from a morphologically novel, highly odorous Streptomyces species which was identified with the species group S. albidoflavus, cluster 1. The new compound, partly responsible for the odour, was assigned the structure of 2R',6,7,7-tetramethyl-1S',8R'- tricyclo-[6.2.1.0(1,5)]undec-5-en-4-one based on spectroscopic studies including 2D NMR (COSY, HETCOR, ROESY, NOE-difference) experiments.

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