2. Academic Validation
  3. Cytotoxicity of Hymenocallis expansa alkaloids

Cytotoxicity of Hymenocallis expansa alkaloids

  • J Nat Prod. 1993 Aug;56(8):1423-5. doi: 10.1021/np50098a030.
M D Antoun 1,  N T Mendoza,  Y R Ríos,  G R Proctor,  D B Wickramaratne,  J M Pezzuto,  A D Kinghorn
Affiliations

Affiliation

  • 1 Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico, San Juan 00936-5067.
PMID: 8229020 DOI: 10.1021/np50098a030
Abstract

From the bulbs and leaves of Hymenocallis expansa (Amaryllidaceae), three alkaloid constituents were identified: (+)-tazettine, (+)-hippeastrine, and (-)-haemanthidine. These Alkaloids demonstrated significant cytotoxicity when tested against a panel of human and murine tumor cell lines.

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