2. Academic Validation
  3. Respinomycins A1, A2, B, C and D, a novel group of anthracycline antibiotics. II. Physico-chemical properties and structure elucidation

Respinomycins A1, A2, B, C and D, a novel group of anthracycline antibiotics. II. Physico-chemical properties and structure elucidation

  • J Antibiot (Tokyo). 1993 Jun;46(6):942-51. doi: 10.7164/antibiotics.46.942.
M Ubukata 1,  J Uzawa,  H Osada,  K Isono
Affiliations

Affiliation

  • 1 Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
PMID: 8344876 DOI: 10.7164/antibiotics.46.942
Abstract

Respinomycins A1, A2, B, C and D were revealed to be novel anthracycline Antibiotics with molecular formulae of C51H72N2O20, C43H58N2O15, C35H43NO14, C36H45NO14 and C51H70N2O22, respectively. Their structures were determined by means of 1H-1H COSY, 13C-1H COSY and HMBC spectra. The structure of the aglycone of respinomycins was unambiguously determined by LSPD experiments and NOESY. The common skeleton of respinomycins is a new type and is distinguished from that of the nogalamycin group.

Figures
Products