2. Academic Validation
  3. Fortimicins A and B, new aminoglycoside antibiotics. I. Producing organism, fermentation and biological properties of fortimicins

Fortimicins A and B, new aminoglycoside antibiotics. I. Producing organism, fermentation and biological properties of fortimicins

  • J Antibiot (Tokyo). 1977 Jul;30(7):533-40. doi: 10.7164/antibiotics.30.533.
T Nara,  M Yamamoto,  I Kawamoto,  K Takayama,  R Okachi,  S Takasawa,  T Sato,  S Sato
PMID: 893224 DOI: 10.7164/antibiotics.30.533
Abstract

A culture of Micromonospora species MK-70 was found to produce two new Antibiotics, fortimicins A and B. Antibacterial and paper chromatographic data on an eluate from IRC-50 treatment of fermentation beers indicated that fortimicins A and B are new Antibiotics with broad-spectrum, basic and water-soluble properties. Fortimicin A exhibited potent, unique, broad-spectrum Antibacterial activity against Gram-positive and negative bacteria both in vitro and in vivo, while fortimicin B was only weakly active.

Figures
Products