2. Academic Validation
  3. Cytotoxic oxygenated desmosterols of the red alga Galaxaura marginata

Cytotoxic oxygenated desmosterols of the red alga Galaxaura marginata

  • J Nat Prod. 1996 Jan;59(1):23-6. doi: 10.1021/np960016w.
J H Sheu 1,  S Y Huang,  C Y Duh
Affiliations

Affiliation

  • 1 Department of Marine Resources, National Sun Yat-Sen University, Taiwan, Republic of China.
PMID: 8984148 DOI: 10.1021/np960016w
Abstract

Desmosterol (1), 24,25-epoxycholesterol (2), 24-hydroperoxycholesta-5,25-dien-3 beta-ol (3), 25-hydroperoxycholesta-5,23(E)-dien-3 beta-ol (4), cholesta-5,25-diene-3 beta,24-diol (5), and 24,25-epoxy-6 beta-hydroxycholest-4-en-3-one (7) were isolated from the marine red alga Galaxaura marginata; sterols 3, 4, and 7 were isolated for the first time from a natural source. Sterols 3-7 exhibited significant cytotoxicity toward several Cancer cell lines.

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