MCH(human, mouse, rat) (Synonyms: Melanin-concentrating hormone(human, mouse, rat))

Cat. No.: HY-P1205: FAQs
Data Sheet Handling Instructions

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MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC₅₀ values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC₅₀ values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively.

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MCH(human, mouse, rat) Chemical Structure

CAS No. : 128315-56-0

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Other Forms of MCH(human, mouse, rat):

MCH(human, mouse, rat) TFA Get quote

1 Publications Citing Use of MCE MCH(human, mouse, rat)

•Adv Sci (Weinh). 2024 Sep 25:e2309951. [Abstract]

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Description	MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC₅₀ values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC₅₀ values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively^[1].
IC₅₀ & Target	Binding IC50: 0.3 nM (MCH1R) IC50: 1.5 nM (MCH1R)^[1]
Molecular Weight	2386.84
Formula	C₁₀₅H₁₆₀N₃₀O₂₆S₄
CAS No.	128315-56-0
Sequence Shortening	DFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (259 KB) Handling Instructions (2659 KB)
References	[1]. A W Sailer, et al. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7564-9. [Content Brief]

MCH(human, mouse, rat) Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCH(human, mouse, rat)128315-56-0Melanin-concentrating hormone(human, mouse, rat)MCHR1 (GPR24)Melanin concentrating hormone receptor 1Inhibitorinhibitorinhibit

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MCH(human, mouse, rat) (Synonyms: Melanin-concentrating hormone(human, mouse, rat))

Other Forms of MCH(human, mouse, rat):

MCH(human, mouse, rat) Related Antibodies

1 Publications Citing Use of MCE MCH(human, mouse, rat)

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•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review