1. Apoptosis
  2. Bcl-2 Family
  3. Mcl-1 inhibitor 9

Mcl-1 inhibitor 9 (example 2) is a myeloid cell leukemia 1 (Mcl-1) inhibitor with IC50 value of 0.21889 nM. Mcl-1 inhibitor 9 shows anti-tumor activity.

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Mcl-1 inhibitor 9 Chemical Structure

Mcl-1 inhibitor 9 Chemical Structure

CAS No. : 1883727-31-8

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Description

Mcl-1 inhibitor 9 (example 2) is a myeloid cell leukemia 1 (Mcl-1) inhibitor with IC50 value of 0.21889 nM. Mcl-1 inhibitor 9 shows anti-tumor activity[1].

In Vitro

Mcl-1 inhibitor 9 (0-22.2 μM; 16 h) inhibits the growth of human multiple myeloma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: OPM-2 cells
Concentration: 0-22.2 μM
Incubation Time: 16 hours
Result: Showed IC50 value of 104.69 nM.
Molecular Weight

599.18

Formula

C32H39ClN2O5S

CAS No.
SMILES

ClC1=CC=C([C@@]2(CCC3)CN4C5=CC(C(NS(=O)([C@@H]([C@H](C/C=C\[C@@H]([C@@]6([H])[C@](CC6)([H])C4)O)C)C)=O)=O)=CC=C5OC2)C3=C1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mcl-1 inhibitor 9
Cat. No.:
HY-148203
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