MCOPPB

Cat. No.: HY-10886: FAQs
Data Sheet Handling Instructions

Molarity Calculator

MCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ–Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB is used in anxiety disorders research.

For research use only. We do not sell to patients.

MCOPPB Chemical Structure

CAS No. : 1028969-49-4

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of MCOPPB:

MCOPPB trihydrochloride

Other Forms of MCOPPB:

MCOPPB trihydrochloride In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Opioid Receptor Isoform Specific Products:

View All Isoforms

μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

Biological Activity
Purity & Documentation
References
Customer Review

Description

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	EC₅₀	34 nM Compound: 1, MCOPPB	Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding	[PMID: 19125610]
CHO-K1	EC₅₀	4696 nM Compound: 1, MCOPPB	Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding	[PMID: 19125610]
HEK293	EC₅₀	0.39 nM Compound: 1, MCOPPB	Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding	[PMID: 19125610]
HEK293	EC₅₀	80 nM Compound: 1, MCOPPB	Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding	[PMID: 19125610]

Molecular Weight

408.62

Formula

C₂₆H₄₀N₄

CAS No.

1028969-49-4

SMILES

CC1(N2CCC(N3C4=CC=CC=C4N=C3[C@H]5CNCCC5)CC2)CCCCCCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hirao A, et al. Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent. J Pharmacol Sci. 2008 Mar;106(3):361-8. [Content Brief]

MCOPPB Related Classifications

Neurological Disease

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCOPPB1028969-49-4Opioid ReceptorNociceptin/orphanin FQ peptide (NOP) receptorVogel conflict testAnxietyInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks