2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. MCPG sodium

MCPG is a carboxylic phenyl glycine. MCPG can block metabotropic glutamate receptor (mGluR)(HY-15129) and has antagonistic activity of mGluR subtype. MCPG can be used to study the induction and maintenance of long-term potentiation (LTP) .

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MCPG sodium Chemical Structure

MCPG sodium Chemical Structure

CAS No. : 1303994-09-3

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MCPG sodium Related Antibodies

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Description

MCPG is a carboxylic phenyl glycine. MCPG can block metabotropic glutamate receptor (mGluR)(HY-15129) and has antagonistic activity of mGluR subtype. MCPG can be used to study the induction and maintenance of long-term potentiation (LTP) [1].

In Vitro

MCPG (300 μM, 1, and 3 mM) inhibits the concentration-dependent increase of phosphoinositol (PPI) hydrolysis induced by 1S, 3R-aminocyclopentane-1, 3-dicarboxic acid (ACPD) in hippocampus sections [1].
MCPG (20 mM, 200 mM) has a selective blocking effect on long-term potentiation (LTP) (20 mM), and also inhibits tetanus-induced short-term potentiation (STP) (200 mM) [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MCPG sodium Related Antibodies
In Vivo

MCPG (Intracerebroventricular injection) can eliminate the enhancement of field excitatory postsynaptic potential (fEPSP) in the alveolar gyrus induced by tedium stimulation in male Wistar rats [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

231.18

Formula

C10H10NNaO4
CAS No.
SMILES

O=C(O[Na])C(C)(N)C1=CC=C(C(O)=O)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MCPG sodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCPG1303994-09-3mGluRMetabotropic glutamate receptorshippocampuslong-term potentiation (LTP)metabotropic glutamate receptor (mGluR)dentate gyrusInhibitorinhibitorinhibit

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