2. Anti-infection
  3. Bacterial
  4. MenA-IN-1

MenA IN-1 is an effective inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB) with an IC50 value of 13 µM and an GIC50 value of 8 µM. MenA IN-1 can be used to curb the continuous spread of tuberculosis.

For research use only. We do not sell to patients.

MenA-IN-1 Chemical Structure

MenA-IN-1 Chemical Structure

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MenA-IN-1 Related Antibodies

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Description

MenA IN-1 is an effective inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB) with an IC50 value of 13 µM and an GIC50 value of 8 µM. MenA IN-1 can be used to curb the continuous spread of tuberculosis[1].

IC50 & Target

IC50: 13 µM (1,4-dihydroxy-2-naphthoate isoprenyltransferase, MenA)[1]
In Vitro

MenA IN-1 (compound 2) (50 µM) has bactericidal effect on Mycobacterium tuberculosis (MTB) and significantly enhances the bactericidal effect when combined with Q203 (HY-101040) or IMP (HY-108213)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MenA-IN-1 Related Antibodies
Molecular Weight

444.61

Formula

C29H36N2O2
SMILES

CCCN(C1=CC=C(C=C1)CN2CCC(CC2)COC3=CC(OC4=CC=CC=C4)=CC=C3)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MenA-IN-1 Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MenA-IN-1BacterialBactericidal effectTuberculosisMycobacterium tuberculosisMTBInhibitorinhibitorinhibit

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HY-152495
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