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  4. Mer-NF5003F

Mer-NF5003F  (Synonyms: Stachybotrydial; F 1839M; Stachybotrydial)

Cat. No.: HY-137985
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Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities. It inhibits avian myeloblastosis virus (AMV) protease (IC50=7.8 μM).1 Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s=0.61, 6.7, and 10 μg/mL, respectively), as well as fucosyltransferase (IC50=11.3 μg/mL). It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50=4.32 μg/mL).3 Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50=0.85 μg/mL).

For research use only. We do not sell to patients.

Mer-NF5003F Chemical Structure

Mer-NF5003F Chemical Structure

CAS No. : 149598-70-9

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Mer-NF5003F Related Antibodies

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Description

Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities. It inhibits avian myeloblastosis virus (AMV) protease (IC50=7.8 μM).1 Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s=0.61, 6.7, and 10 μg/mL, respectively), as well as fucosyltransferase (IC50=11.3 μg/mL). It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50=4.32 μg/mL).3 Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50=0.85 μg/mL).

Molecular Weight

386.48

Formula

C23H30O5
CAS No.
SMILES

O[C@@H]1CC[C@]2([C@]([H])(C1(C)C)CC[C@H]([C@@]23OC4=C(C3)C(O)=CC(C=O)=C4C=O)C)C
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Mer-NF5003F Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mer-NF5003F149598-70-9Stachybotrydial F 1839M StachybotrydialHSVHerpes simplex virusInhibitorinhibitorinhibit

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