meso-Benzothiazole-BODIPY 505/515 

meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeautophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases^[1].

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs)^[1].
Labeling of Cells:
1. Culture cells in 20 mm confocal dishes at a density of 5× 10⁴ cells/mL. Incubate the cells according to your normal protocol.
2. For confocal imaging, adding 5 μM meso-Benzothiazole-BODIPY 505/515 (Probe 1) in medium are used to culture the cells for 30 min.
3. Cells are excited at 488 nm and emissions were collected at 520 600 nm.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

381.25

C₂₀H₁₈BF₂N₃S

[F-][B+3]1([F-])[N]2=C(C=C(C2=C(C3=C(C=C([N-]31)C)C)C4=NC5=CC=CC=C5S4)C)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wen-Jing Shi, et al. Novel Meso-Benzothiazole-Substituted BODIPY-Based AIE Fluorescent Rotor for Imaging Lysosomal Viscosity and Monitoring Autophagy. Anal Chem. 2022 Oct 12.  [Content Brief]