2. Anti-infection
  3. Bacterial Beta-lactamase
  4. Metallo-β-lactamase-IN-12

Metallo-β-lactamase-IN-12 is a dual inhibitor of metal β-lactamases (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC50 values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity.

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Metallo-β-lactamase-IN-12 Chemical Structure

Metallo-β-lactamase-IN-12 Chemical Structure

CAS No. : 3028594-43-3

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Metallo-β-lactamase-IN-12 Related Antibodies

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Description

Metallo-β-lactamase-IN-12 is a dual inhibitor of metal β-lactamases (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC50 values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity[1].

IC50 & Target

IC50: 0.64 μM (NDM-1)[1].
IC50: 1.32 μM (IMP-1)[1].
IC50: 1.01 μM (OXA-48)[1].
IC50: 0.57 μM (KPC-2)[1].
Molecular Weight

313.35

Formula

C18H19NO4
CAS No.
SMILES

O=C(ONC(CCCC1=CC=CC=C1)=O)OCC2=CC=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Metallo-β-lactamase-IN-12 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metallo-β-lactamase-IN-123028594-43-3BacterialBeta-lactamaseβ-lactamaseSerine β-lactamaseMetallo-β-lactamaseAntibacterial agentAntibioticInhibitorinhibitorinhibit

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