1. Immunology/Inflammation
  2. CD73
  3. MethADP sodium

MethADP sodium  (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate sodium)

Cat. No.: HY-112502B
Handling Instructions

MethADP (sodium salt) (Adenosine 5'-(α,β-methylene)diphosphate (sodium)) is a specific CD73 inhibitor.

For research use only. We do not sell to patients.

MethADP sodium Chemical Structure

MethADP sodium Chemical Structure

CAS No. : 89016-30-8

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Description

MethADP (sodium salt) (Adenosine 5'-(α,β-methylene)diphosphate (sodium)) is a specific CD73 inhibitor.

IC50 & Target

CD73[1].

In Vitro

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formula

C11H17N5O9P2.xNa

CAS No.
SMILES

O[C@@H]1[C@H](O)[C@@H](COP(O)(CP(O)(O[Na])=O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N.[x].[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MethADP sodium
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HY-112502B
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