MethADP sodium (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate sodium)

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MethADP (sodium salt) (Adenosine 5'-(α,β-methylene)diphosphate (sodium)) is a specific CD73 inhibitor.

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MethADP sodium Chemical Structure

CAS No. : 89016-30-8

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Other Forms of MethADP sodium:

MethADP Get quote
MethADP disodium Get quote
MethADP triammonium Get quote

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Description	MethADP (sodium salt) (Adenosine 5'-(α,β-methylene)diphosphate (sodium)) is a specific CD73 inhibitor.
IC₅₀ & Target	CD73^[1].
In Vitro	MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. MethADP sodium Related Antibodies
Formula	C₁₁H₁₇N₅O₉P₂.xNa
CAS No.	89016-30-8
SMILES	O[C@@H]1[C@H](O)[C@@H](COP(O)(CP(O)(O[Na])=O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N.[x].[Na]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202. [Content Brief]

MethADP sodium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MethADP89016-30-8Adenosine 5'-(α,β-methylene)diphosphateCD73ecto-5′-nucleotidase, NT5EInhibitorinhibitorinhibit

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MethADP sodium (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate sodium)

Other Forms of MethADP sodium:

MethADP sodium Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review