1. Anti-infection Neuronal Signaling Immunology/Inflammation GPCR/G Protein
  2. Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor
  3. Methicillin sodium hydrate

Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis.

For research use only. We do not sell to patients.

Methicillin sodium hydrate Chemical Structure

Methicillin sodium hydrate Chemical Structure

CAS No. : 7246-14-2

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Description

Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis[1].

IC50 & Target

β-lactam

 

In Vitro

Methcillin sodium hydrate (20 μg/mL, 24 h) results in a rapid decrease in CFU of S. aureus[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Methicillin sodium hydrate (Intramuscular administration, 40 mg/kg every 6 h, 5 days), in S. aureus.-infected rabbits[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

420.41

Formula

C17H21N2NaO7S

CAS No.
SMILES

O=C(O[Na])[C@H](N1C2=O)C(C)(S[C@@]1([C@@H]2NC(C3=C(C=CC=C3OC)OC)=O)[H])C.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Methicillin sodium hydrate
Cat. No.:
HY-121544A
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