2. PROTAC
  3. PROTAC Linkers
  4. Methyl 3-hydroxypropanoate

Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Methyl 3-hydroxypropanoate Chemical Structure

Methyl 3-hydroxypropanoate Chemical Structure

CAS No. : 6149-41-3

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Based on 1 publication(s) in Google Scholar

Methyl 3-hydroxypropanoate Related Antibodies

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Description

Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Methyl 3-hydroxypropanoate Related Antibodies
Molecular Weight

104.10

Formula

C4H8O3
CAS No.
Appearance

Liquid (Density: 1.1050 g/cm3)

Color

Colorless to off-white

SMILES

O=C(OC)CCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.83%

COA (243 KB) HNMR (114 KB) GC (233 KB)

Handling Instructions (2659 KB)
References
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Methyl 3-hydroxypropanoate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyl 3-hydroxypropanoate6149-41-3PROTAC LinkersInhibitorinhibitorinhibit

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Product Name:
Methyl 3-hydroxypropanoate
Cat. No.:
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