1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. TRP Channel
  3. Methyl kakuol

Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM.

For research use only. We do not sell to patients.

Methyl kakuol Chemical Structure

Methyl kakuol Chemical Structure

CAS No. : 70342-29-9

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Description

Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1].

IC50 & Target[1]

TRPA1

 

In Vivo

The maximum concentration (Cmax) of Methyl kakuol at a dose of 2 g/kg (containing 1156 µg/kg, 294 µg/kg, 452 µg/kg, 852 µg/kg asarinin, sesamin, methyl kakuol, and amide A, respectively) is 98.2 ng/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

208.21

Formula

C11H12O4

CAS No.
SMILES

O=C(C(C=C(OCO1)C1=C2)=C2OC)CC

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Methyl kakuol
Cat. No.:
HY-N7965
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