Methyl-triphenylphosphonium-d₃ bromide

Name: Methyl-triphenylphosphonium-d 3 bromide
Brand: MedChemExpress
SKU: HY-Y1033S
Rating: 4.5 (1 reviews)

Cat. No.: HY-Y1033S Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Methyl-triphenylphosphonium-d₃ (bromide) is the deuterium labeled Methyl-triphenylphosphonium bromide[1].

For research use only. We do not sell to patients.

Methyl-triphenylphosphonium-d<sub>3</sub> bromide Chemical Structure

Methyl-triphenylphosphonium-d₃ bromide Chemical Structure

CAS No. : 1787-44-6

Size	Stock	Quantity
1 mg	Get quote	Estimated Time of Arrival: December 31
5 mg	Get quote	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Methyl-triphenylphosphonium-d₃ (bromide) is the deuterium labeled Methyl-triphenylphosphonium bromide[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

360.24

Formula

C₁₉H₁₅D₃BrP

CAS No.

1787-44-6

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (277.59 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7759 mL	13.8796 mL	27.7593 mL
5 mM	0.5552 mL	2.7759 mL	5.5519 mL
10 mM	0.2776 mL	1.3880 mL	2.7759 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (276 KB) SDS (393 KB)

COA (256 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.7759 mL	13.8796 mL	27.7593 mL	69.3982 mL
	5 mM	0.5552 mL	2.7759 mL	5.5519 mL	13.8796 mL
	10 mM	0.2776 mL	1.3880 mL	2.7759 mL	6.9398 mL
	15 mM	0.1851 mL	0.9253 mL	1.8506 mL	4.6265 mL
	20 mM	0.1388 mL	0.6940 mL	1.3880 mL	3.4699 mL
	25 mM	0.1110 mL	0.5552 mL	1.1104 mL	2.7759 mL
	30 mM	0.0925 mL	0.4627 mL	0.9253 mL	2.3133 mL
	40 mM	0.0694 mL	0.3470 mL	0.6940 mL	1.7350 mL
	50 mM	0.0555 mL	0.2776 mL	0.5552 mL	1.3880 mL
	60 mM	0.0463 mL	0.2313 mL	0.4627 mL	1.1566 mL
	80 mM	0.0347 mL	0.1735 mL	0.3470 mL	0.8675 mL
	100 mM	0.0278 mL	0.1388 mL	0.2776 mL	0.6940 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.